Pain is the primary symptom in a range of health conditions. Poorly managed acute or chronic pain may negatively influence numerous aspects of a person’s life. However, managing pain adequately remains a challenge in many conditions1. For mild to moderate pains, NSAIDs (non-steroidal anti-inflammatory drugs) remain the mainstay of treatment. NSAIDs like ibuprofen have some …
Pharmacology and Toxicology of Tramadol & Tapentadol Read More »
Tramadol, Tapentadol and Soma are primarily FDA approved Schedule II and Schedule IV medications prescribed for moderate to severe pain. Though the exact mechanism is not clear, Tapentadol and Tramadol are believed to work by inhibiting the serotonin reuptake, i.e. blocking the pathways involved in the transmission of pain. Soma works on the GABA receptors …
In 1995, a chemical entity was released by Janssen pharmaceutical which is known as Tramadol (Ultram). Again in 2009, a similar entity was released by Janssen called Tapentadol (Nucynta). Tapentadol was released as a schedule II analgesic which was the first new opioid entity with controlled substance status. It was approved by the Food and …
Synopsis We are going through the Covid-19 pandemic caused by novel coronavirus originated in Wuhan province, China. The numbers of cases are on the rise since 31st December 2019. It has been observed that Covid-19 patients often complain of muscular pain along with stomach pain, joint pain, and testicular pain. In a few rare cases, …
What are the Pain Manifestations in Covid-19 Patients? Read More »
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